A 58-year-old woman presents with 6 months of symmetrical pain and stiffness in the small joints of her hands and feet, worse in the morning for over ...

Question

A 58-year-old woman presents with 6 months of symmetrical pain and stiffness in the small joints of her hands and feet, worse in the morning for over an hour. Examination shows synovitis of the MCPs and PIPs. RF and anti-CCP antibodies are positive. What is the most appropriate initial disease-modifying treatment?

Accepted Answer

Methotrexate

Answer

Paracetamol alone

Answer

Long-term high-dose prednisone alone

Answer

Azathioprine first-line

Answer

Celecoxib only

au-amc MCQ (SBA): Rheumatoid arthritis