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COPD — SCE Respiratory MCQ

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HardGlobal Strategy for COPDCOPDSCE Respiratory

A woman of child-bearing age has progressive dyspnoea, recurrent pneumothoraces, diffuse thin-walled lung cysts and a renal angiomyolipoma. Which diagnosis is most likely?

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Correct answer: A — Lymphangioleiomyomatosis

The combination of diffuse cystic lung disease, recurrent pneumothorax and angiomyolipoma in a woman strongly suggests lymphangioleiomyomatosis. VEGF-D can support diagnosis in the right radiological context; specialist assessment considers sirolimus for abnormal or declining lung function and pleural recurrence prevention.

Reference: https://www.nice.org.uk/guidance/conditions-and-diseases/respiratory-conditions