Pulmonary Embolism (Subsegmental) — SCE Respiratory MCQ
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Correct answer: A — Start oral oseltamivir now despite five days of symptoms
The 48-hour threshold applies mainly to otherwise uncomplicated community illness. Hospitalised or severely unwell patients with influenza should receive prompt neuraminidase-inhibitor treatment even when symptom onset was more than 48 hours earlier; dose and duration are adapted to renal function and clinical course.
Reference: UKHSA guidance on influenza antiviral treatment and prophylaxis (Current UKHSA guidance, accessed 30 July 2026): https://www.gov.uk/government/publications/influenza-treatment-and-prophylaxis-using-anti-viral-agents; BNF monograph for oseltamivir (Current BNF monograph, accessed 30 July 2026): https://bnf.nice.org.uk/drugs/oseltamivir/