sodium hydrogen carbonate + terpeneless dill seed oil: clinical use

Prescribing considerations

• Confirm crying is consistent with wind-related distress and assess for feeding problems, reflux, constipation, allergy, infection or other illness.
• Evidence supporting gripe water for infant colic is limited; persistent or atypical symptoms need clinical assessment.
• Consider exposure to sodium, propylene glycol, maltitol and parahydroxybenzoates, including from other products.

Contraindications and cautions

• Age under 1 month or 1 year and over.
• Impaired kidney function.
• Hypersensitivity to either active ingredient, hydroxybenzoates or another excipient.
• Metabolic or respiratory alkalosis, hypocalcaemia or hypochloraemia.
• Hereditary fructose intolerance, because the formulation contains maltitol.

Monitoring

• No routine monitoring is specified for licensed use; review persistent symptoms.
• Following substantial overdose, assess fluid, electrolyte and acid-base status, with circulatory and neurological monitoring where indicated.

Clinical pharmacology

Sodium hydrogen carbonate has antacid activity. Dill seed oil is an aromatic carminative used for flatulence; product-specific pharmacokinetic data are not provided.

Formulation and product differences

• The selected product is an alcohol-free, sugar-free oral solution but contains maltitol.
• It also contains propylene glycol, sodium and parahydroxybenzoate preservatives.
• Store below 25°C and use within 14 days after opening.