nicotinamide at a glance
Medicine class
Topical vitamin B3 derivative with anti-inflammatory activity
Licensed use
Mild to moderate inflammatory acne vulgaris
What is nicotinamide used for?
The selected product is licensed for topical treatment of mild to moderate inflammatory acne vulgaris, including inflamed papules and pustules.
Mild to moderate inflammatory acne vulgaris
How does nicotinamide work?
Nicotinamide contributes to the coenzymes NAD and NADP, which support cellular oxidation-reduction reactions. Its benefit in inflammatory acne is thought to relate mainly to local anti-inflammatory activity; it is not an antibiotic.
nicotinamide preparations and strengths
Gel
Route: Cutaneous
Strengths: 4% w/w
nicotinamide side effects
Common or expected effects
- Dry skin
- Itching
- Redness
- Burning sensation
- Local irritation
nicotinamide in pregnancy
The product information states that there are no specific pregnancy restrictions or known potential risks, but advises caution, particularly during the first trimester. Discuss use with a pharmacist, doctor or midwife if pregnant or planning pregnancy.
nicotinamide while breastfeeding
The patient leaflet gives no specific restriction on topical use during breastfeeding, although nicotinamide can enter breast milk after systemic exposure. Ask a healthcare professional for advice, particularly before applying it near the breast.
nicotinamide interactions
No interactions with other medicines are known for the selected topical product.
Other medicines
No medicine interactions are identified in the current product information.
Common questions about nicotinamide
Answers are fully visible for fast scanning and source review.
What is topical nicotinamide used for?
The selected product is licensed for mild to moderate inflammatory acne vulgaris.
Is nicotinamide the same as niacinamide?
Yes. Niacinamide is another name for nicotinamide, the amide form of vitamin B3.
Is nicotinamide an antibiotic?
Sources
These sources were used to prepare and review this medicine page.
Prepared and reviewed by the iatroX editorial team.