magnesium chloride hexahydrate + potassium chloride + procaine hydrochloride at a glance
Medicine class
Cardioplegic electrolyte and local-anaesthetic combination.
Clinical setting
Used only in hospital during heart surgery involving cardiopulmonary bypass.
Administration
A trained cardiac-surgery professional dilutes the concentrate immediately before coronary-artery infusion.
What is magnesium chloride hexahydrate + potassium chloride + procaine hydrochloride used for?
Its UK-licensed use is to induce cardioplegia during heart surgery.
Infusion into the coronary arteries during cardiopulmonary bypass to produce controlled temporary cardiac arrest.
How does magnesium chloride hexahydrate + potassium chloride + procaine hydrochloride work?
Potassium changes the electrical potential of heart-muscle cells to produce depolarised arrest. Magnesium slows cardiac conduction, while procaine acts locally on the myocardium to reduce electrical excitability, conduction and contraction. Together these effects make the heart still during surgery.
How to take magnesium chloride hexahydrate + potassium chloride + procaine hydrochloride
This product is not taken by the patient. It is prepared immediately before use and administered during surgery by a medically competent professional trained in open-heart procedures.
It is a concentrate and must be diluted with the specified Compound Sodium Chloride Injection before use.
It is infused into the coronary circulation during cardiopulmonary bypass.
magnesium chloride hexahydrate + potassium chloride + procaine hydrochloride side effects
Get urgent medical advice
- Rare severe allergic reaction, with difficulty breathing or swallowing or swelling of the face, lips, tongue or throat.
- Excessive exposure may cause apnoea, circulatory depression or seizures. These lists are not exhaustive.
magnesium chloride hexahydrate + potassium chloride + procaine hydrochloride in pregnancy
The product information provides no medicine-specific pregnancy data. Pregnancy should be disclosed to the cardiac surgical and anaesthetic teams so that the overall need for surgery and perioperative treatment can be assessed.
magnesium chloride hexahydrate + potassium chloride + procaine hydrochloride while breastfeeding
The product information provides no medicine-specific breastfeeding data. Breastfeeding should be discussed with the surgical and anaesthetic teams as part of planning care around the operation.
magnesium chloride hexahydrate + potassium chloride + procaine hydrochloride interactions
No specific medicine interactions are stated in the SmPC. The clinical team should nevertheless know about all prescribed, non-prescription and complementary products being used.
Common questions about magnesium chloride hexahydrate + potassium chloride + procaine hydrochloride
Answers are fully visible for fast scanning and source review.
What is magnesium chloride hexahydrate, potassium chloride and procaine hydrochloride used for?
It is used during heart surgery to induce cardioplegia—a controlled temporary arrest of the heart.
Is magnesium chloride hexahydrate, potassium chloride and procaine hydrochloride taken by mouth?
No. It is a hospital-only concentrate administered into the coronary circulation during surgery.
Sources
These sources were used to prepare and review this medicine page.
Prepared and reviewed by the iatroX editorial team.