Influenza virus inactivated split (H1N1, H3N2-like, b/brisbane/60/2008-like, strains) at a glance
Class
Inactivated split-virion influenza vaccine
Main role
Prevention, not treatment, of seasonal influenza
Administration
Injection into a muscle; subcutaneous administration is also licensed
Protection
Protection is not immediate and may not be complete
What is Influenza virus inactivated split (H1N1, H3N2-like, b/brisbane/60/2008-like, strains) used for?
Licensed uses represented by Vaxigrip include:
Active immunisation against influenza in adults, including pregnant women, and children from 6 months of age.
Passive protection of babies from birth to under 6 months through antibodies transferred after vaccination during pregnancy.
How does Influenza virus inactivated split (H1N1, H3N2-like, b/brisbane/60/2008-like, strains) work?
Inactivated components from selected influenza A and B strains stimulate antibodies that help the body recognise and neutralise matching viruses. Maternal antibodies can cross the placenta and temporarily protect the baby.
How to take Influenza virus inactivated split (H1N1, H3N2-like, b/brisbane/60/2008-like, strains)
A trained healthcare professional gives the injection. Tell them about serious allergic reactions, fever, immune-suppressing treatment, bleeding disorders or fainting with needles.
The healthcare professional should bring the suspension towards room temperature, shake it and visually inspect it before use.
It must not be injected into a blood vessel.
Other vaccines given at the same visit require separate syringes and injection sites.
Influenza virus inactivated split (H1N1, H3N2-like, b/brisbane/60/2008-like, strains) side effects
Common or expected effects
- Injection-site pain, redness, hardness or swelling
- Headache, muscle aches or feeling unwell
- Mild fever, shivering or tiredness
- In younger children, irritability, drowsiness, reduced appetite or unusual crying
Get urgent medical advice
- Severe allergic reaction
- Convulsions or progressive weakness, altered sensation or paralysis
- Unusual bleeding or bruising associated with reduced platelets
- Inflammation of blood vessels, sometimes involving the kidneys
Influenza virus inactivated split (H1N1, H3N2-like, b/brisbane/60/2008-like, strains) in pregnancy
Vaxigrip is licensed throughout pregnancy and may provide early protection for the baby through transferred antibodies. Seasonal guidance determines which inactivated product is preferred.
Influenza virus inactivated split (H1N1, H3N2-like, b/brisbane/60/2008-like, strains) while breastfeeding
Vaxigrip may be used while breastfeeding. Discuss product choice with the vaccinating clinician if there is a history of serious vaccine allergy or other significant medical concerns.
Influenza virus inactivated split (H1N1, H3N2-like, b/brisbane/60/2008-like, strains) interactions
Relevant considerations include:
Other vaccines
They may be given at the same visit when appropriate, using separate syringes and injection sites.
Immunosuppressants, cytotoxic treatment or radiotherapy
The immune response may be reduced, although the inactivated vaccine cannot replicate and cause influenza.
Common questions about Influenza virus inactivated split (H1N1, H3N2-like, b/brisbane/60/2008-like, strains)
Answers are fully visible for fast scanning and source review.
Can this vaccine give me flu?
No. It contains no live influenza virus. Short-lived fever, aches or tiredness may occur after vaccination.
Can it be given with other vaccines?
Yes, when clinically appropriate, using separate syringes and injection sites.
Does it protect against every flu virus or a common cold?
Sources
These sources were used to prepare and review this medicine page.
Prepared and reviewed by the iatroX editorial team.