ethyl nicotinate + hexyl nicotinate + tetrahydrofurfuryl salicylate at a glance
Medicine class
Topical rubefacient containing nicotinates and a salicylate.
Route
Applied externally to intact skin and gently massaged until absorbed.
Usual role
Symptomatic relief of rheumatic or muscular pain and sprains or strains.
Product status
Transvasin Heat Rub Cream is listed as discontinued.
What is ethyl nicotinate + hexyl nicotinate + tetrahydrofurfuryl salicylate used for?
This topical cream is used for symptomatic relief of:
Rheumatic pain
Muscular pain
Symptoms of sprains and strains
How does ethyl nicotinate + hexyl nicotinate + tetrahydrofurfuryl salicylate work?
Ethyl nicotinate and hexyl nicotinate increase local skin redness and create warmth. Tetrahydrofurfuryl salicylate contributes to topical treatment of musculoskeletal, joint and soft-tissue symptoms.
How to take ethyl nicotinate + hexyl nicotinate + tetrahydrofurfuryl salicylate
For external use only. Gently massage into the affected area until absorbed, following the pack instructions. Use only on intact, non-sensitive skin. Avoid the eyes, mucous membranes and genital skin. Wash your hands afterwards, avoid airtight dressings and avoid excessive sunlight on treated skin.
Stop using it if a rash develops.
Keep it out of the sight and reach of children.
ethyl nicotinate + hexyl nicotinate + tetrahydrofurfuryl salicylate side effects
Common or expected effects
- Warmth and skin redness shortly after application are expected effects and do not necessarily indicate intolerance.
- Local rash, sensitisation or contact dermatitis can occur. Stop use if a rash develops.
Get urgent medical advice
- Call 999 for swelling of the lips, mouth, tongue or throat, severe wheezing or breathing difficulty, fainting or collapse.
ethyl nicotinate + hexyl nicotinate + tetrahydrofurfuryl salicylate in pregnancy
Product-specific evidence is limited. Seek advice from a pharmacist, midwife or prescriber before using this salicylate-containing cream during pregnancy.
ethyl nicotinate + hexyl nicotinate + tetrahydrofurfuryl salicylate while breastfeeding
Product-specific evidence is limited. Ask a pharmacist or prescriber before use, prevent the baby touching treated skin and wash your hands before handling or feeding the baby.
ethyl nicotinate + hexyl nicotinate + tetrahydrofurfuryl salicylate interactions
Tell a pharmacist or prescriber about anticoagulant treatment before using this cream.
Warfarin
Topical salicylates have been reported to increase warfarin's anticoagulant effect, potentially increasing bleeding risk.
Common questions about ethyl nicotinate + hexyl nicotinate + tetrahydrofurfuryl salicylate
Answers are fully visible for fast scanning and source review.
Why can the skin feel hot and look red?
The nicotinate ingredients deliberately produce local warmth and redness. These effects alone do not necessarily indicate intolerance.
Can I use it if I am allergic to aspirin or NSAIDs?
No. It is contraindicated with known hypersensitivity to aspirin, other salicylates or NSAIDs, particularly when associated with asthma.
Can it be used on broken or irritated skin?
Sources
These sources were used to prepare and review this medicine page.
Prepared and reviewed by the iatroX editorial team.