dexketoprofen trometamol at a glance
Medicine class
NSAID; a propionic acid derivative.
Licensed uses
Musculoskeletal pain, painful periods and dental pain.
Form
Scored, film-coated tablet that can be divided into equal halves.
Age
Safety and effectiveness have not been established in children or adolescents.
What is dexketoprofen trometamol used for?
The selected UK tablet is licensed for symptomatic treatment of mild to moderate pain.
Musculoskeletal pain
Painful periods
Dental pain
How does dexketoprofen trometamol work?
Dexketoprofen inhibits COX-1 and COX-2 enzymes, reducing prostaglandins involved in pain and inflammation. Trometamol is the salt form; dexketoprofen is the active pain-relieving component.
dexketoprofen trometamol preparations and strengths
Tablet
Route: Oral
Strengths: 25 mg
How to take dexketoprofen trometamol
Follow the prescription label and swallow the tablet with sufficient water. Food delays absorption, so follow the product instructions or prescriber's advice about meals. The tablet can be divided into equal halves. Do not drive or operate machinery if you experience dizziness, drowsiness or visual disturbance.
Do not combine it with another NSAID unless specifically directed by a clinician.
Avoid becoming dehydrated because this can increase the risk of kidney problems.
dexketoprofen trometamol side effects
Common or expected effects
- Nausea or vomiting
- Abdominal pain
- Diarrhoea
- Indigestion
Get urgent medical advice
- Stomach or intestinal ulceration, bleeding or perforation
- Severe allergic reaction, including bronchospasm, facial or throat swelling and anaphylaxis
- Severe blistering skin reactions or fixed drug eruption
- Acute kidney injury or marked fluid retention
- Chest pain associated with an allergic reaction
- Possible heart attack or stroke symptoms
dexketoprofen trometamol in pregnancy
Dexketoprofen should only be considered during the first and second trimesters when clearly necessary and advised by a prescriber. Systemic NSAIDs should generally be avoided from 20 weeks because of risks to fetal kidney function, amniotic fluid and the ductus arteriosus. Dexketoprofen is contraindicated during the third trimester.
dexketoprofen trometamol while breastfeeding
The selected UK product is contraindicated during breastfeeding because it is unknown whether dexketoprofen enters human milk. Ask a prescriber about an alternative; specialist guidance identifies ibuprofen or diclofenac as preferred NSAIDs for full-term, healthy breastfed infants.
dexketoprofen trometamol interactions
Check all prescribed, pharmacy and over-the-counter products because some combination remedies contain NSAIDs.
Other NSAIDs, COX-2 inhibitors or salicylates
Combining them increases the risk of gastrointestinal ulceration and bleeding.
Warfarin, heparins and other anticoagulants
Bleeding risk may increase; combinations require avoidance or close clinical and laboratory monitoring.
Corticosteroids, antiplatelets and SSRIs
These can further increase the risk of gastrointestinal ulceration or bleeding.
Common questions about dexketoprofen trometamol
Answers are fully visible for fast scanning and source review.
Is dexketoprofen trometamol the same as ibuprofen?
No. Both are NSAIDs, but they contain different active ingredients. They should not usually be taken together because combining NSAIDs increases adverse effects.
Does food affect dexketoprofen trometamol?
Food delays absorption but does not change overall exposure. Follow the product instructions or prescriber's advice about meals.
Sources
These sources were used to prepare and review this medicine page.
Prepared and reviewed by the iatroX editorial team.