cetrimide + lidocaine hydrochloride monohydrate + zinc sulfate: clinical use

Prescribing considerations

• Confirm that symptoms follow an insect bite, sting or plant-contact reaction; this product is not suitable for animal bites.
• Cutaneous use only; not recommended below 12 years because data are insufficient.
• Propylene glycol may cause skin irritation.

Contraindications and cautions

• Known hypersensitivity to any active substance or excipient

Monitoring

• No product-specific laboratory monitoring is specified.
• Review if irritation, sensitisation, worsening symptoms or other unwanted effects occur.

Clinical pharmacology

Lidocaine is an amide local anaesthetic that inhibits sensory impulse conduction. Cetrimide is a quaternary ammonium antiseptic, while zinc sulfate provides astringent and soothing activity. The product acts locally; lidocaine absorption is slower through intact skin than through mucous membranes.

Formulation and product differences

• The licence covers a colourless, viscous gel with a menthol odour marketed under Bites & Stings Pain Relief Gel and Antiseptic and Pain Relief Gel names.