celiprolol hydrochloride at a glance
Medicine class
Beta-1 selective blocker with partial beta-2 agonist activity
Licensed use
Treatment of hypertension; Celectol specifically describes mild to moderate hypertension
Food
Food reduces absorption, so take it on an empty stomach according to the product leaflet
Citrus juice
Avoid citrus juices because they can substantially reduce absorption
What is celiprolol hydrochloride used for?
The selected UK products are licensed for:
High blood pressure in adults
Celectol specifically describes mild to moderate hypertension
How does celiprolol hydrochloride work?
Celiprolol mainly blocks beta-1 receptors, reducing the heart’s response to stress hormones. Partial beta-2 agonist activity may gently widen blood vessels. Together, these actions lower blood pressure and limit the rise in heart rate during exertion.
celiprolol hydrochloride preparations and strengths
Tablet
Route: Oral
Strengths: 200 mg, 400 mg
How to take celiprolol hydrochloride
Follow the dispensing label and the leaflet supplied with your product.
Swallow the tablet with water.
Take it on an empty stomach; products differ slightly in their precise instructions about food.
Avoid citrus juices.
Do not stop suddenly unless directed by a clinician.
Tell the anaesthetist or responsible dentist before an operation that you take celiprolol.
celiprolol hydrochloride side effects
Common or expected effects
- Dizziness, headache, tiredness or sleepiness
- Tremor or pins and needles
- Flushing, sweating, or cold hands and feet
- Nausea, vomiting, abdominal discomfort or dry mouth
- Rash or itching
- Low mood
- Difficulty getting or maintaining an erection
Get urgent medical advice
- Allergic reaction with facial or throat swelling, or difficulty breathing
- Wheezing, bronchospasm or marked breathlessness
- Fainting or a very slow or irregular heartbeat
- Worsening heart failure, including breathlessness and peripheral swelling
- A lupus-like illness with joint symptoms, photosensitivity or other systemic features
celiprolol hydrochloride in pregnancy
Celiprolol should be used during pregnancy only when no safer alternative is suitable. Treatment should be reviewed promptly; fetal-growth surveillance and newborn observation may be considered because beta-blockade can occasionally affect growth, heart rate, breathing or blood glucose.
celiprolol hydrochloride while breastfeeding
The selected product information does not recommend celiprolol while breastfeeding because milk-transfer and infant-safety data are insufficient. Labetalol, metoprolol and propranolol are preferred beta-blockers for a full-term, healthy infant. Continuing celiprolol requires individual clinical assessment and infant monitoring.
celiprolol hydrochloride interactions
Important examples include:
Theophylline
Concomitant use is contraindicated in the selected products and may reduce celiprolol absorption.
Verapamil or diltiazem
Combined effects can slow cardiac conduction, reduce contractility and cause hypotension; avoidance or close ECG monitoring is generally required.
Common questions about celiprolol hydrochloride
Answers are fully visible for fast scanning and source review.
Is celiprolol hydrochloride the same as Celectol?
Celectol is a brand containing celiprolol hydrochloride. Generic products contain the same active ingredient but may differ in tablet appearance and excipients.
Why must it be taken away from food?
Food reduces absorption, which may make its effect less reliable. Follow the food instructions supplied with your product.
Sources
These sources were used to prepare and review this medicine page.
Prepared and reviewed by the iatroX editorial team.