calcium chloride dihydrate + glucose monohydrate + lactic acid + magnesium chloride hexahydrate + potassium chloride + sodium chloride + sodium hydrogen carbonate at a glance
Medicine class
Electrolyte and bicarbonate solution for continuous renal replacement therapy.
Usual role
Replacement or dialysis fluid for kidney failure; it can also support removal of filterable or dialysable poisons.
Potassium context
Intended for people whose blood potassium is within the normal range.
Administration
Used with suitable extracorporeal renal-replacement equipment under specialist supervision.
What is calcium chloride dihydrate + glucose monohydrate + lactic acid + magnesium chloride hexahydrate + potassium chloride + sodium chloride + sodium hydrogen carbonate used for?
Licensed uses include:
Replacement fluid during continuous haemofiltration or haemodiafiltration for kidney failure.
Dialysis fluid during continuous haemodialysis or haemodiafiltration for kidney failure.
Supporting removal of poisons that can pass through the dialysis membrane or filter.
Use in patients with a normal blood-potassium concentration.
How does calcium chloride dihydrate + glucose monohydrate + lactic acid + magnesium chloride hexahydrate + potassium chloride + sodium chloride + sodium hydrogen carbonate work?
Its water, glucose and electrolytes provide a physiologically compatible exchange fluid while filtration or dialysis removes water and dissolved substances from the blood. Bicarbonate and lactate help maintain acid–base balance.
How to take calcium chloride dihydrate + glucose monohydrate + lactic acid + magnesium chloride hexahydrate + potassium chloride + sodium chloride + sodium hydrogen carbonate
This is not swallowed or self-administered. Healthcare professionals combine the two compartments before use, check that the solution is clear and the bag and seals are intact, then connect it to appropriate renal-replacement equipment. If warming is needed, dry heat is used before reconstitution; the bag must not be warmed in water or a microwave.
Use under the direction of a clinician experienced in continuous renal replacement therapy.
Do not use an incompletely mixed, cloudy, discoloured, leaking or damaged bag.
Any additive must be assessed for compatibility and mixed before connection to the circuit.
calcium chloride dihydrate + glucose monohydrate + lactic acid + magnesium chloride hexahydrate + potassium chloride + sodium chloride + sodium hydrogen carbonate side effects
Common or expected effects
- No effects have an established common frequency. Reported effects of unknown frequency include nausea, vomiting, muscle cramps and low blood pressure.
Get urgent medical advice
- Electrolyte disturbances, including low phosphate or abnormal potassium levels.
- Metabolic alkalosis or acidosis.
- Fluid overload or dehydration.
- High blood glucose, particularly in people with diabetes.
- Raised ionised calcium.
- A serious hypersensitivity reaction.
calcium chloride dihydrate + glucose monohydrate + lactic acid + magnesium chloride hexahydrate + potassium chloride + sodium chloride + sodium hydrogen carbonate in pregnancy
Adequate pregnancy data are unavailable. A specialist should assess the benefits and risks; kidney disease requiring renal-replacement therapy also makes pregnancy higher risk and usually needs multidisciplinary obstetric and renal care.
calcium chloride dihydrate + glucose monohydrate + lactic acid + magnesium chloride hexahydrate + potassium chloride + sodium chloride + sodium hydrogen carbonate while breastfeeding
Adequate information about use during breastfeeding is unavailable. The prescriber should assess the benefits and risks for the breastfeeding parent and infant before treatment.
calcium chloride dihydrate + glucose monohydrate + lactic acid + magnesium chloride hexahydrate + potassium chloride + sodium chloride + sodium hydrogen carbonate interactions
Continuous filtration or dialysis can change medicine concentrations, while accompanying treatments may alter electrolyte or acid–base risks.
Filterable or dialysable medicines
Their blood concentrations may fall during treatment, so clinical effect or concentrations may need review.
Digitalis medicines, including digoxin
Low potassium increases the risk of digitalis-related abnormal heart rhythms.
Vitamin D, vitamin D analogues and calcium-containing products
Combined use can increase the risk of high blood calcium.
Common questions about calcium chloride dihydrate + glucose monohydrate + lactic acid + magnesium chloride hexahydrate + potassium chloride + sodium chloride + sodium hydrogen carbonate
Answers are fully visible for fast scanning and source review.
Why is this formulation selected for someone with normal potassium?
It contains potassium and is licensed specifically for normokalaemic patients; it is contraindicated in hyperkalaemia.
Can it be used to remove a medicine or poison?
Yes, when the substance can cross the dialysis membrane or filter. Specialists must assess suitability for the substance involved.
Sources
These sources were used to prepare and review this medicine page.
Prepared and reviewed by the iatroX editorial team.