ascorbic acid + glucose monohydrate + nicotinamide + pyridoxine + riboflavin + thiamine at a glance
Medicine class
High-potency, water-soluble vitamin combination.
Administration
Diluted and given into a vein by a healthcare professional; it is not an oral supplement.
Key safety issue
Rare but potentially severe allergic reactions can occur during or shortly after infusion.
Important interaction
Its pyridoxine component can reduce levodopa’s effect.
What is ascorbic acid + glucose monohydrate + nicotinamide + pyridoxine + riboflavin + thiamine used for?
Licensed uses include:
Rapid treatment of severe depletion or malabsorption of vitamins B and C, particularly in alcohol dependence where severe thiamine depletion may cause Wernicke’s encephalopathy.
Severe vitamin depletion associated with acute infection, postoperative illness or psychiatric states.
Maintaining vitamins B and C in people receiving chronic intermittent haemodialysis.
How does ascorbic acid + glucose monohydrate + nicotinamide + pyridoxine + riboflavin + thiamine work?
The infusion directly replaces several water-soluble vitamins. B vitamins support energy metabolism and nervous-system function. Intravenous administration bypasses impaired intestinal absorption and makes the vitamins rapidly available.
How to take ascorbic acid + glucose monohydrate + nicotinamide + pyridoxine + riboflavin + thiamine
Healthcare professionals combine equal volumes from two labelled ampoules, dilute the mixture in a compatible infusion fluid and administer it into a vein.
Do not inject or administer it yourself.
Tell staff immediately if sneezing, chest tightness, wheezing, rash, dizziness or swelling occurs.
Tell the clinical team about allergies, previous reactions to thiamine injections and all other medicines.
ascorbic acid + glucose monohydrate + nicotinamide + pyridoxine + riboflavin + thiamine side effects
Common or expected effects
- Reported effects with unknown frequency include pain or swelling at the infusion site, pins and needles, low blood pressure, rash and hives.
Get urgent medical advice
- Anaphylaxis or another severe hypersensitivity reaction, causing wheezing, breathing difficulty, facial or throat swelling, severe itching, faintness or loss of consciousness.
ascorbic acid + glucose monohydrate + nicotinamide + pyridoxine + riboflavin + thiamine in pregnancy
No adverse effects have been reported during clinically indicated use, but reproductive evidence is limited and potential human risk is uncertain. Discuss pregnancy or plans for pregnancy with the prescriber.
ascorbic acid + glucose monohydrate + nicotinamide + pyridoxine + riboflavin + thiamine while breastfeeding
Tell the clinical team if you are breastfeeding. Evidence about transfer into breast milk is limited, so the prescriber should assess the treatment need and the infant’s circumstances.
ascorbic acid + glucose monohydrate + nicotinamide + pyridoxine + riboflavin + thiamine interactions
Tell the clinical team about prescribed, non-prescribed and complementary products.
Levodopa
Pyridoxine in the infusion may interfere with levodopa’s therapeutic effect.
Common questions about ascorbic acid + glucose monohydrate + nicotinamide + pyridoxine + riboflavin + thiamine
Answers are fully visible for fast scanning and source review.
Why is it used in alcohol dependence?
Alcohol dependence, poor nutrition and malabsorption can severely deplete thiamine. Parenteral replacement addresses deficiency when oral absorption may be inadequate and Wernicke’s encephalopathy is a concern.
Is it the same as an over-the-counter multivitamin?
No. It is a prescription high-potency intravenous preparation for severe depletion, malabsorption or specific dialysis-related replacement, not routine dietary supplementation.
Sources
These sources were used to prepare and review this medicine page.
Prepared and reviewed by the iatroX editorial team.