Multiple Sclerosis (MS)

Overview and management of MS.

Reviewed by Dr Kola Tytler MBBS CertHE MBA MSt MRCGP (General Practitioner)

Last reviewed: 21 October 2025

Turn this into CPDPractise this topic, identify learning gaps and prepare a CPD draft you can review.Find reviewed question practiceChoose your examination. iatroX will check for an exact reviewed question set before offering a topic; no filter or session starts automatically.

regional clinical guidance

Multiple Sclerosis (MS): guidance by region

Recommendations, thresholds and pathways can differ. Open the page written for the jurisdiction you need.

United StatesMultiple sclerosis diagnosis and disease-modifying careNeurology · reviewed 2026-08-20 CanadaMultiple sclerosisNeurology · reviewed 2026-08-20 AustraliaMultiple sclerosisNeurology · reviewed 2026-08-20

Clinical Guidelines

NHS: Treatment Algorithm for Multiple Sclerosis Disease-Modifying Therapies

NICE CKS: Multiple sclerosis

NICE guideline [CG186]: Multiple sclerosis in adults: management

NICE guideline [NG220]: Multiple sclerosis in adults: management

NICE: Multiple sclerosis in adults: management

2019 CMSC Practical Guidelines for the Selection of Disease Modifying Therapies in Multiple Sclerosis

Consensus recommendations on multiple sclerosis management in Australia and New Zealand

EAN guideline on palliative care of people with severe, progressive multiple sclerosis

European and American Guidelines for Multiple Sclerosis Treatment

Multiple sclerosis in adults: management (NICE guideline NG220)

Occupational Therapy Practice Guidelines for Adults With Multiple Sclerosis (AOTA, 2022)

Practice Guideline Recommendations: Disease-modifying Therapies for Adults with Multiple Sclerosis (AAN, 2018, reaffirmed 2024)

Practice guideline update summary: Vaccine-preventable infections and immunization in multiple sclerosis (AAN, 2019)

UK consensus on pregnancy in multiple sclerosis: 'Association of British Neurologists and UK MS Specialist Nurses consensus guidelines'