Macrocytosis

Investigation of large red blood cells (high MCV).

Reviewed by Dr Kola Tytler MBBS CertHE MBA MRCGP (General Practitioner)
Last reviewed: 21 October 2025
Haematology

Clinical Guidelines

A004 - ADULT PATIENTS WITH MACROCYTOSIS (Norfolk and Norwich University Hospitals NHS Foundation Trust)
National
Macrocytosis
National
Macrocytosis - Adult CPC | SA Health
National
Macrocytosis (Guidelines) | Right Decisions (NHS Highland)
National
Macrocytosis (isolated) – RefHelp (NHS Lothian)
National
Macrocytosis (Remedy BNSSG ICB)
National
Macrocytosis guidelines (Sheffield CCG Portal)
National
ESPEN micronutrient guideline
Local
European Consensus on the Diagnosis and Management of Iron Deficiency and Anaemia in Inflammatory Bowel Diseases
Local
Evaluation of Macrocytosis | AAFP
Local
International Recommendations for Screening and Preventative Practices in Chronic Graft-versus-Host Disease
Local
KDIGO Clinical Practice Guideline for Anemia in Chronic Kidney Disease (2012)
Local
The European Guidelines on Diagnosis and Management of Neutropenia
Local
Vitamin B12 deficiency in over 16s: diagnosis and management; NICE guideline [NG239]
Local