Hyponatraemia

Investigation and management of low sodium.

Reviewed by Dr Kola Tytler MBBS CertHE MBA MSt MRCGP (General Practitioner)

Last reviewed: 21 October 2025

NephrologyEndocrinology

Turn this into CPDPractise this topic, identify learning gaps and prepare a CPD draft you can review.Find reviewed question practiceChoose your examination. iatroX will check for an exact reviewed question set before offering a topic; no filter or session starts automatically.

regional clinical guidance

Hyponatraemia: guidance by region

Recommendations, thresholds and pathways can differ. Open the page written for the jurisdiction you need.

United StatesAdult hyponatremia: diagnosis and safe correctionEndocrine & metabolic · reviewed 2026-08-20 CanadaHyponatraemiaEndocrine & metabolic · reviewed 2026-08-20 AustraliaHyponatraemiaEndocrine & metabolic · reviewed 2026-08-20

Clinical Guidelines

CKS: Hyponatraemia

CKS: Management of Hyponatraemia

Emergency management of severe and moderately severely symptomatic hyponatraemia in adult patients

ESE Clinical guideline for the management of hyponatraemia

Management of Hyponatraemia Clinical Guideline V3.0 July 2024

NICE guideline [NG180]

Clinical practice guideline on diagnosis and treatment of hyponatraemia (European Society of Endocrinology, European Renal Association–European Dialysis and Transplant Association, European Society of Intensive Care Medicine, 2014)

Consensus document on the management of hyponatraemia of the Spanish Society of Endocrinology and Nutrition (SEEN)

Emergency management of severe and moderately severely symptomatic hyponatraemia in adult patients (Society for Endocrinology, 2022)

ESE Clinical guideline for the management of hyponatraemia

European Society of Endocrinology Clinical Practice Guideline on Diagnosis and Treatment of Hyponatraemia (2014)

Wilderness Medical Society Clinical Practice Guidelines for the Prevention and Treatment of Exercise-Associated Hyponatremia (2019)