skip to main content

Chronic Fatigue Syndrome (ME/CFS)

Diagnosis and management of ME/CFS.

Reviewed by Dr Kola Tytler MBBS CertHE MBA MSt MRCGP (General Practitioner)
Last reviewed: 21 October 2025
General PracticeNeurology
Turn this into CPDPractise this topic, identify learning gaps and prepare a CPD draft you can review.Find reviewed question practiceChoose your examination. iatroX will check for an exact reviewed question set before offering a topic; no filter or session starts automatically.
regional clinical guidance

Chronic Fatigue Syndrome (ME/CFS): guidance by region

Recommendations, thresholds and pathways can differ. Open the page written for the jurisdiction you need.

United StatesME/CFS recognition and symptom-prioritized careMental health · reviewed 2026-08-20CanadaME/CFS (myalgic encephalomyelitis/chronic fatigue syndrome): evidence and source overviewMental health · reviewed 2026-08-20AustraliaME/CFS (myalgic encephalomyelitis/chronic fatigue syndrome)Mental health · reviewed 2026-08-20

Clinical Guidelines

Chronic fatigue syndrome/myalgic encephalomyelitis (or encephalopathy): diagnosis and management
National
CKS: Myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS)
National
NICE guideline [NG206]
National
NICE guideline [NG206]: Myalgic encephalomyelitis (or encephalopathy)/chronic fatigue syndrome: diagnosis and management
National
Beyond Myalgic Encephalomyelitis/Chronic Fatigue Syndrome: Redefining an Illness (Institute of Medicine Report 2015)
Local
NICE guideline [NG206]: Myalgic encephalomyelitis (or encephalopathy)/chronic fatigue syndrome (ME/CFS): diagnosis and management
Local
US ME/CFS Clinician Coalition Consensus Statement: Diagnosing Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) in Patients with Post-COVID Conditions
Local