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Anaemia (B12 and Folate Deficiency)

Investigation and treatment of macrocytic anaemias.

Reviewed by Dr Kola Tytler MBBS CertHE MBA MSt MRCGP (General Practitioner)
Last reviewed: 21 October 2025
HaematologyGeneral Practice
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regional clinical guidance

Anaemia (B12 and Folate Deficiency): guidance by region

Recommendations, thresholds and pathways can differ. Open the page written for the jurisdiction you need.

United StatesVitamin B12 and folate deficiency anemiaHematology · reviewed 2026-08-20CanadaAnaemia: vitamin B12 and folate deficiencyHaematology · reviewed 2026-08-20AustraliaAnaemia: vitamin B12 and folate deficiencyHaematology · reviewed 2026-08-20

Clinical Guidelines

NICE Clinical Knowledge Summary: Anaemia - B12 and folate deficiency
National
NICE guideline [NG239]: Vitamin B12 deficiency in over 16s: diagnosis and management
National
NICE Clinical Knowledge Summary: Anaemia - B12 and folate deficiency
Local
NICE guideline [NG239]: Vitamin B12 deficiency in over 16s: diagnosis and management
Local