Answer
Yes, St John's wort is contraindicated with Emtricitabine/Rilpivirine/Tenofovir Alafenamide Gilead because it can significantly decrease rilpivirine plasma concentrations, potentially causing loss of therapeutic effect.
Sources for this answer
- Emtricitabine/Rilpivirine/Tenofovir Alafenamide Gilead 200 mg/25 mg/25 mg film-coated tabletsGilead Sciences Ltd · emc · SmPC §4.3 Contraindications · Version 24Document updated
Sources checked