Answer
Yes. It is very common when treatment begins and often becomes less troublesome as the body adjusts. Discuss persistent or severe headache with a clinician.
Sources for this answer
- NHSNHS · NHS medicine guidance
- Isosorbide Dinitrate Tablets 20 mg — Current selected SmPCemc · Summary of Product Characteristics
General medicine information. Follow the instructions for your own medicine and speak to a pharmacist or clinician about your individual circumstances.