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Medicines isosorbide dinitrateQuestion & answer

isosorbide dinitrate · Medicine question

Can sildenafil or tadalafil be taken with it?

iatroX medicinesPublished 20 August 2026Reviewed 20 August 2026

The answer

Answer

No. Combining PDE-5 inhibitors with nitrates can cause a dangerous fall in blood pressure.

Sources for this answer

Isosorbide Dinitrate Tablets 20 mgemc · SmPC Current selected SmPC · Version 2
Isoket Retard 20 Tabletsemc · SmPC Current selected SmPC · Version 6

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The full medicine guide

isosorbide dinitrate

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