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Medicines sotorasibQuestion & answer

sotorasib · Medicine question

Is diarrhoea a common side effect of sotorasib?

iatroX medicinesPublished 8 November 2026

The answer

Answer

Yes, diarrhoea is a very common side effect of sotorasib (Lumykras), reported in 36.6% of patients in the cited clinical studies.

Sources for this answer

LUMYKRAS 240 mg film-coated tabletsAmgen Ltd · emc · SmPC §4.8 Undesirable effects · Version 3Document updated 15 July 2026

Sources checked 8 November 2026

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The full medicine guide

sotorasib

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