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Medicines aprotinin + calcium chloride dihydrate + human fibrinogen + human thrombinQuestion & answer

aprotinin + calcium chloride dihydrate + human fibrinogen + human thrombin · Medicine question

Is aprotinin + calcium chloride dihydrate + human fibrinogen + human thrombin a surgical glue?

iatroX medicinesPublished 18 August 2026Reviewed 18 August 2026

The answer

Answer

Yes. It is a two-component fibrin tissue sealant that forms a clot-like adhesive when its components mix.

Sources for this answer

ARTISS Solutions for Sealantemc · SmPC Current selected SmPC · Version 5

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The full medicine guide

aprotinin + calcium chloride dihydrate + human fibrinogen + human thrombin

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What is aprotinin + calcium chloride dihydrate + human fibrinogen + human thrombin used for?Can aprotinin + calcium chloride dihydrate + human fibrinogen + human thrombin replace stitches or staples?Is aprotinin + calcium chloride dihydrate + human fibrinogen + human thrombin injected?Why must previous aprotinin or ARTISS exposure be reported?Does aprotinin + calcium chloride dihydrate + human fibrinogen + human thrombin contain human blood products?Can aprotinin + calcium chloride dihydrate + human fibrinogen + human thrombin transmit infection?