Answer
Adapalene absorption through human skin is low; with Differin Gel, no measurable plasma levels were found after chronic application to large areas of acne-affected skin at an analytical sensitivity of 0.15 ng/ml.
Sources for this answer
- Differin GelGalderma (U.K.) Limited · emc · SmPC §5.2 Pharmacokinetic properties · Version 16Document updated
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