Answer
Adapalene binds specific retinoic acid nuclear receptors and is thought to normalise follicular epithelial cell differentiation, reducing microcomedone formation, while its anti-inflammatory activity helps reduce inflammatory acne lesions such as papules and pustules.
Sources for this answer
- Differin CreamGalderma (U.K.) Limited · emc · SmPC §5.1 Pharmacodynamic properties · Version 17Document updated
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