Answer
After oral administration, flutamide is rapidly and extensively absorbed and almost completely metabolised, with rapid, extensive conversion to metabolites, principally hydroxyflutamide, which has potent anti-androgenic activity.
Sources for this answer
- Flutamide 250 mg TabletsViatris (formerly Mylan or Upjohn) · emc · SmPC §5.2 Pharmacokinetic properties · Version 4Document updated
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