Answer
Starting flutamide monotherapy can increase prothrombin time in patients receiving chronic warfarin treatment, so careful monitoring is recommended and the anticoagulant dose may need adjustment.
Sources for this answer
- Flutamide 250 mg TabletsViatris (formerly Mylan or Upjohn) · emc · SmPC §4.5 Interaction with other medicinal products · Version 3Document updated
Sources checked