How is clobetasol propionate thought to be metabolised and excreted after absorption through the skin from clobetasol propionate + neomycin + nystatin cream?

After skin absorption from clobetasol propionate + neomycin + nystatin cream, clobetasol propionate probably follows systemic corticosteroid metabolism, primarily in the liver followed by kidney excretion, although its systemic metabolism has never been fully characterised or quantified.