zanubrutinib · Medicine question

How does zanubrutinib inhibit Bruton's tyrosine kinase (BTK)?

iatroX medicinesPublished 8 November 2026

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Zanubrutinib inhibits Bruton's tyrosine kinase (BTK) by forming a covalent bond with a cysteine residue in the BTK active site, thereby inhibiting BTK activity.

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BRUKINSA 80 mg hard capsulesBeOne Medicines UK, Ltd. · emc · SmPC §5.1 Pharmacodynamic properties · Version 9Document updated 20 October 2026

Sources checked 8 November 2026

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