Answer
Vipdomet lowers blood glucose in type 2 diabetes through alogliptin, which inhibits DPP-4 to enhance insulin release and suppress glucagon when glucose is high, and metformin, which may reduce liver glucose production, modestly improve muscle insulin sensitivity and glucose uptake, and delay intestinal glucose absorption.
Sources for this answer
- Alogliptin/Metformin Hydrochloride 12.5 mg/1000 mg film-coated tabletsTakeda UK Ltd · emc · SmPC §5.1 Pharmacodynamic properties · Version 12Document updated
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