Answer
Vipdomet’s metformin component may reduce vitamin B12 levels, with risk increasing at higher doses, with longer treatment or existing deficiency risk factors; levels should be monitored if deficiency is suspected, and periodic monitoring may be needed in patients with risk factors.
Sources for this answer
- Alogliptin/Metformin Hydrochloride 12.5 mg/1000 mg film-coated tabletsTakeda UK Ltd · emc · SmPC §4.4 Special warnings and precautions for use · Version 12Document updated
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