Answer
Although its mechanism is not definitively established, vinblastine sulfate appears to bind to or crystallise critical microtubular proteins of the mitotic spindle, preventing proper polymerisation and arresting cell division at metaphase.
Sources for this answer
- Vinblastine Sulfate 1 mg/ml InjectionHospira UK Ltd · emc · SmPC §5.1 Pharmacodynamic properties · Version 18Document updated
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