Answer
VeraSeal initiates the final phase of clotting by converting fibrinogen into fibrin monomers that aggregate into a clot, with thrombin-activated factor XIIIa crosslinking fibrin and calcium ions required for both fibrinogen conversion and fibrin crosslinking.
Sources for this answer
- VeraSealGrifols UK Ltd · emc · SmPC §5.1 Pharmacodynamic properties · Version 5Document updated
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