Answer
In adults, trimethoprim/sulfamethoxazole 160 mg/800 mg increases lamivudine exposure by 40% because of trimethoprim, while sulfamethoxazole does not interact; no lamivudine dosage adjustment is necessary unless the patient has renal impairment.
Sources for this answer
- Epivir Oral SolutionViiV Healthcare UK Ltd · emc · SmPC §4.5 Interaction with other medicinal products · Version 45Document updated
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