Answer
Terbinafine strongly inhibits CYP2D6 and may increase exposure to and accumulation of clomipramine hydrochloride and its N-demethylated metabolite, so clomipramine dose adjustments may be necessary when they are taken together.
Sources for this answer
- Clomipramine 25 mg Capsules, HardViatris (formerly Mylan or Upjohn) · emc · SmPC §4.5 Interaction with other medicinal products · Version 2Document updated
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