Answer
In hydrochlorothiazide + telmisartan, telmisartan tends to reverse hydrochlorothiazide-related potassium loss, presumably through blockade of the renin–angiotensin–aldosterone system, and decreases plasma aldosterone levels.
Sources for this answer
- MicardisPlus 80 mg/25 mg TabletsBoehringer Ingelheim Limited · emc · SmPC §5.1 Pharmacodynamic properties · Version 24Document updated
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