Answer
Talzenna (talazoparib) inhibits PARP1 and PARP2 catalytic activity and traps PARP proteins at DNA lesions, preventing DNA repair, replication and transcription and thereby causing apoptosis and/or cell death.
Sources for this answer
- Talzenna 1mg Hard CapsulesPfizer Limited · emc · SmPC §5.1 Pharmacodynamic properties · Version 10Document updated
Sources checked