Answer
Streptozocin spontaneously decomposes into reactive methylcarbonium ions that alkylate DNA, causing interstrand cross-links and strand breaks, with severe DNA damage resulting in cell death by apoptosis or necrosis.
Sources for this answer
- Zanosar 1 g, powder for concentrate for solution for infusionEsteve Pharmaceuticals (formerly Intrapharm Laboratories) · emc · SmPC §5.1 Pharmacodynamic properties · Version 2Document updated
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