Answer
Saxagliptin hydrochloride inhibits DPP4, increasing active incretin hormones GLP-1 and GIP, enhancing glucose-dependent insulin release and decreasing glucagon, thereby lowering fasting and post-meal blood glucose in people with type 2 diabetes.
Sources for this answer
- Onglyza 5mg film-coated tabletsAstraZeneca UK Limited · emc · SmPC §5.1 Pharmacodynamic properties · Version 26Document updated
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