Answer
Rifampin, a strong CYP3A inducer, reduces systemic exposure (AUCinf) to zuranolone by 85%, potentially reducing its efficacy, so concomitant use should be avoided.
Sources for this answer
- Zurzuvae 20 mg, 25 mg and 30 mg Hard CapsulesBiogen Idec Ltd · emc · SmPC §4.5 Interaction with other medicinal products · Version 2Document updated
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