Answer
Ramipril lowers blood pressure through its active metabolite, ramiprilat, which inhibits angiotensin-converting enzyme (ACE), reducing angiotensin II formation and bradykinin breakdown so blood vessels widen and peripheral arterial resistance falls.
Sources for this answer
- Ramipril Aurobindo 5 mg TabletsAurobindo Pharma - Milpharm Ltd. · emc · SmPC §5.1 Pharmacodynamic properties · Version 9Document updated
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