Answer
Posaconazole inhibits lanosterol 14α-demethylase (CYP51), the enzyme that catalyses an essential step in fungal ergosterol biosynthesis.
Sources for this answer
- Noxafil 40mg/ml oral suspensionMerck Sharp & Dohme (UK) Limited · emc · SmPC §5.1 Pharmacodynamic properties · Version 30Document updated
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