Answer
Paricalcitol selectively upregulates vitamin D receptors and calcium-sensing receptors in the parathyroid glands, inhibiting parathyroid proliferation and decreasing parathyroid hormone synthesis and secretion, with minimal impact on calcium and phosphorus levels.
Sources for this answer
- Zemplar 5 microgram/ml Solution for InjectionAbbVie Ltd · emc · SmPC §5.1 Pharmacodynamic properties · Version 24Document updated
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