Answer
Mitotane alters extra-adrenal cortisol metabolism in humans, reducing measurable 17-hydroxy corticosteroids even though plasma corticosteroid levels do not fall.
Sources for this answer
- Mitotane Esteve 500 mg TabletsEsteve Pharmaceuticals (formerly Intrapharm Laboratories) · emc · SmPC §5.1 Pharmacodynamic properties · Version 2Document updated
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