Answer
Linezolid inhibits bacterial protein synthesis by binding to the 23S site of the bacterial ribosome’s 50S subunit, preventing formation of the functional 70S initiation complex essential for translation.
Sources for this answer
- Zyvox 2 mg/ml Solution for InfusionPfizer Limited · emc · SmPC §5.1 Pharmacodynamic properties · Version 8Document updated
Sources checked