Answer
Letermovir increases oral midazolam plasma concentrations 2–3-fold through CYP3A inhibition, with the magnitude of inhibition depending on letermovir's route of administration and concomitant ciclosporin use.
Sources for this answer
- PREVYMIS 240 mg film-coated tabletsMerck Sharp & Dohme (UK) Limited · emc · SmPC §4.5 Interaction with other medicinal products · Version 14Document updated
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