Answer
Ledipasvir/sofosbuvir increases tenofovir blood concentrations when taken with emtricitabine/tenofovir disoproxil, especially when the HIV regimen also contains a pharmacokinetic enhancer such as ritonavir or cobicistat.
Sources for this answer
- Emtricitabine/Tenofovir disoproxil Dr. Reddy's 200 mg/245 mg Film-Coated TabletsDr. Reddy's Laboratories (UK) Ltd · emc · SmPC §4.4 Special warnings and precautions for use · Version 11Document updated
Sources checked