Answer
In healthy subjects, co-administration of multiple doses of itraconazole oral solution containing 8 g hydroxypropyl-beta-cyclodextrin per dose with 40 mg asciminib hydrochloride decreased asciminib exposure (AUCinf) by 40.2%.
Sources for this answer
- Scemblix 20 mg and 40 mg film-coated tabletsNovartis Pharmaceuticals UK Ltd · emc · SmPC §5.2 Pharmacokinetic properties · Version 8Document updated
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