Answer
Asciminib hydrochloride inhibits the ABL1 kinase activity of the BCR::ABL1 fusion protein by specifically targeting the ABL myristoyl pocket.
Sources for this answer
- Scemblix 20 mg and 40 mg film-coated tabletsNovartis Pharmaceuticals UK Ltd · emc · SmPC §5.1 Pharmacodynamic properties · Version 8Document updated
Sources checked