How does iron dextran replenish haemoglobin and depleted iron stores after intravenous administration?

After intravenous infusion, iron dextran is taken up by reticuloendothelial cells, particularly in the liver and spleen, which split the complex and slowly release iron that binds to proteins as ferritin, hemosiderin or, to a lesser extent, transferrin, replenishing haemoglobin and depleted iron stores under physiological control.